Unusual Symptoms

Lab Test July 24, 2013 Lyme IgM antibodies Western Blot - page 1

IGeneX interpretation is based on internal validation studies. By IGeneX criteria, IgM WB is considered positive if two or more of the double starred bands below are present. The IgM WB is considered negative if less than 2 starred bands are present. A positive result suggests exposure to B burgdorferi. By CDC/NYS criteria, IgM WB is reported positive if 2 of the following bands are present: 23-25, 39, 41kDa. The IgM WB is negative if less than 2 bands are present.

LIMITATION: Positive result for 31 and/or 34kDa may be present after Lyme vaccination in uninfected persons. Positive result with proteins at 31, 41 and/or 83kDa may be due to non-specific binding of viral or other spirochetal antibodies.

****PRESENCE OF ONLY ONE DOUBLE STARRED BAND OR INDETERMINATE DOUBLE STARRED BANDS IN A NEGATIVE REPORT MAY INDICATE CLINICAL SIGNIFICANCE.

****THEREFORE, WE RECOMMEND TESTING WITH ANOTHER METHOD AND/OR RETEST IN 4-6 WEEKS.

BAND INTENSITY:

Negative (-): No band detected.

Indeterminate (IND): Band present with intensity < calibration standard.

Positive (1+ - 4+): Band present at an intensity >= to calibration standard.

IGENEX IGM RESULT: POSITIVE

CDC/NYS RESULT: NEGATIVE

Diagnosis should not be based on laboratory tests alone. Results should be interpreted in conjunction with clinical symptoms and patient history.