Unusual Symptoms

Lab Test May 29, 2013 Detoxgenomic Profile - page 10


CYP2C9

Down regulator - detoxifies coumarin and sufionylureas.
Note: Individuals with deficient CYP2C9 activity may be anti-coagulated on 0.5mg of coumadin/day, as they cannot efficiently clear S-coumadin. ARBs in these people may be ineffective because a pro-drug like losartan may be poorly activated.

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