| Substrates | Inhibitors | Inducers | ||
|---|---|---|---|---|
| NSAIDs Diciofenac Ibuprofen Lomoxicam Meloxicam S-Naproxen Piroxicam Suprofen Oral Hypoglycemic Agents Tolbutamide Glipizide Angiotensin II Blockers Losartan Irbesartan Sulfonylureas Glyburide/glibenclamide Gilpizide Gilmepiride Tolbutamide Miscellaneous Alosetron (Lotronex) Amitrptyline (Elavil) (demethylation) Angiotensin Carvedilol Celecoxib Chloramphenicol Clomipramine Coumadin (Warfarin) Desogestrel Diazepam Diclofenac Dronabinol Etravirine |
Miscellaneous Continued Febuxostat Fluoxetine Flurbiprofen Fluvastatin Formoterol Glyburide Hexobarbital Hyzaar Ibuprofen Imipramine (Tofranil) Indomethacin Isonizid Nateglinide Phenobarbital Phenytoin (Dilantin) Piroxicam Retinoids Roosiglitazone Rosuvastatin (Crestor) Sildenafil (Viagra) Sulfa Drugs Sulfaphenazole Suprofen Tamoxifen THC (marijuana) Torsemide (Demadex) Valdecoxib S-warfarin (active) Zolpidem (Ambien, Edluar) (mostly CYP3A4) |
Anti- depressants Fluvoxamine (Luvox) Paroxetine (Paxil) Sertraline (Zoloft) Fluoxetine (Prozac) Azole Antifungals Itraconazole (Sporonox) Ketoconazole (Nizoral) Fluconazol (Diflucan) Miconazole (Nystatin) Voriconazole (Vfend) Miscellaneous Amiodarone Cimetidine (Tagamet) Chloram- phenicol Clopidotgrel (Plavix) Delavirdine Disulfram Efavirenz Etravirine Fenofibrate Fluorouracil Fluvastatin Gemfibrozil |
Miscellaneous Continued Imatinib Isoniazid Leflunomide Lovastatin Metronidazole (Flagyl) Omeprazole Phenylbutazone Phenytoin (Dilantin) Probenicid Retonavir (Norvir) Sulfa- methoxazole Trimethoprim (Bactrim) Sulfaphenazole Sulfinpyrazone Teniposide> Ticlopidine Valproic acid (Depakote) Zafirlukast Echinacea Garlic (possible) Kava kava Milk thistle (in-vitro/ probably insignificant in-vivo) Saw palmetto (in-vitro) St. John's wort (in-vitro studies |
Aminoglutethimide Aprepitant Barbiturates Bosentan Carbamazepiine Ethanol Griseovulfin Phenobarbital Phenytoin Primidone Rifabutin Rifampin Rifapentine Secobarbital |
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