(COMT SNP) higher risk for depression, bipoler disorder, ADHD and alcoholism.

(NAT SNP) both slow and rapid acetylators are at increased risk for developing lung, colon, bladder, or head & neck cancer

(GST SNP) The GST isforms (M1, PP1, and T1) are more or less prevalent in various tisues, all catalyze the conjugation of electrophilic compounds with glutathion. Defects in GST activity can contribute to fatigue syndromes and to various cancers throughout the body.

(SOD SNP) SOD1 is present in the cytosol; SOD2 is present in the mitochodria. Changes in the SOD enzyme are associated with changes in risk for neurodegenerative disorders like ALS

Your Results: Catechol-O-methyl transferase is the enzyme primarily responsible for breaking down the neurotransmitters dopamine, epinephrine, and norepinephrine.

Your Results: N-acetyl Transferase detoxifies many environmental toxins, including tobacco smoke and exhaust fumes. Polymorphisms can result in slower than normal or faster than normal addition of an acetyl group to these toxins. Slow acetylators have a build up of toxins in the system and rapid aceylators add acetyl groups so rapidly that they make mistakes in the process. Both slow and rapid aceylators are at increased risk for toxic overload if they are exposed to environmental toxins. If the toxin exposure is reduced, the risk is reduced.

Your Results: Glutathione-S-transferase detoxifies many water-soluable environmental toxins, including many solvents, herbicides, fungicides, lipid peroxides, and heavy metals (e.g., mercury, cadmium, and lead). The various forms of GST work together to eliminate toxins. Decreased glutathione conjugation capacity may increase toxic burden and increase oxidative stress.

Your results: Superoxide Dismutase is an enzyme that protects cells from increased oxidative stress and free radical damage to cell structures like membranes, mitochondria, DNA, and proteins.